CFTR: New Members Join the Fold
نویسنده
چکیده
The folding, misfolding, and degradation of membrane proteins is controlled by multiple processes within the cell. In this issue of Cell, Wang et al. (2006) present an interactome for CFTR, the chloride channel that is misfolded and prematurely degraded in cystic fibrosis. Among the proteins interacting with CFTR is a new member of the Hsp90 chaperone system, Aha1, that plays a central role in CFTR folding.
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ورودعنوان ژورنال:
- Cell
دوره 127 شماره
صفحات -
تاریخ انتشار 2006